Suxamethonium Apnoea
Description:
Prolonged effect of Suxamethonium, which means a patient may reverse from anaesthesia,
but remain paralysed. As the patient becomes aware, blood pressure and heart rate increase,
the patient may sweat, and the pupils may dilate. A nerve stimulator can show whether the
patient is still paralysed and, if so, the patient should be re-anaesthetised and ventilated.
Caused by inability to metabolise Suxamethonium, due to insufficient Pseudocholinesterase
in the blood.
Treatment: Anaesthetise and ventilate the patient; monitor for
Train of four.
Acquired Suxamethonium Apnoea:
Acquired Suxamethonium Apnoea is when the action of Suxamethonium lasts for hours,
rather than minutes, and can occur in the presence of...
- Anticholinesterases
- Carcinomatosis
- Cardiopulmonary bypass
- Hypothyroidism
- Liver disease
- Methotrexate
- Pregnancy
- Renal disease
- Monoamine oxidase inhibitors